reverse transcriptase inhibitor(redirected from Nucleotide analogs)
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reverse transcriptase inhibitor
n. Abbr. RTI
Any of various antiviral compounds that interfere with the activity of the enzyme reverse transcriptase, which is found especially in retroviruses such as HIV. These compounds are divided into two classes: those that are nucleoside analogs (nucleoside reverse transcriptase inhibitors) and those that are not nucleoside analogs (non-nucleoside reverse transcriptase inhibitors).
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|Noun||1.||reverse transcriptase inhibitor - an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV|
NNRTI, non-nucleoside reverse transcriptase inhibitor - an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs