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Related to O-linked glycosylation: N-linked glycosylation


The addition of saccharides to proteins or lipids to form a glycoprotein or glycolipid.

[glycose, a monosaccharide (variant of glucose) + -yl + -ation.]

gly·co′sy·late′ v.


(Biochemistry) the process by which sugars are chemically attached to proteins to form glycoproteins
[from glycosyl radical derived from glycose + -ation]
References in periodicals archive ?
Mutahons in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial humoral calcinosis.
In the precursor structure, the midregion (proBNP 36-71) contains 7 serine and threonine residues, where O-linked glycosylation occurs either fully or partially (Fig.
11) reported O-linked glycosylation of proBNP that hampers antibody recognition (12).
Of particular interest to later discussion are signals shifted up in mass by 162, 203, and 657 Da, suggesting glycation (Glyc), O-linked glycosylation (GalNAc), and a second O-linked glycoform ([NeuNAc.
It is critical to determine whether the circulating BNP forms have posttranslational modifications (PTM), such as phosphorylation or N- and O-linked glycosylation, and/or bind to other protein(s).