ACTH

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ACTH

 (ā′sē′tē′āch′)
n.
A hormone produced by the anterior lobe of the pituitary gland that stimulates the secretion of cortisol and other hormones by the adrenal cortex. Also called adrenocorticotropin, corticotropin.

[a(dreno)c(ortico)t(ropic) h(ormone).]

ACTH

n
(Biochemistry) adrenocorticotrophic hormone; a polypeptide hormone, secreted by the anterior lobe of the pituitary gland, that stimulates growth of the adrenal gland and the synthesis and secretion of corticosteroids. It is used in treating rheumatoid arthritis, allergic and skin diseases, and many other disorders. Also called: corticotrophin

ACTH

a hormone of the anterior pituitary that stimulates the production of steroids in the cortex of the adrenal glands.
Also called adrenocorticotropic hormone, adrenocorticotropin.
[1940–45; a(dreno)c(ortico)t(ropic)h(ormone)]

ACTH

(ā′sē′tē-āch′)
Short for adrenocorticotropic hormone. A hormone secreted by a lobe of the pituitary gland. It stimulates the adrenal glands to produce cortisone and related hormones.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ACTH - a hormone produced by the anterior pituitary gland that stimulates the adrenal cortexACTH - a hormone produced by the anterior pituitary gland that stimulates the adrenal cortex
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
Translations

ACTH

abbr adrenocorticotropic hormone. V. hormone.
References in periodicals archive ?
For example, what physiological purpose is served by the POMC neurons' ability to switch from repressing hunger to amplifying it?
Extensive evidence suggests that both the POMC and NPY have a critical impact on the early oneset of metabolic syndrome features in children, as well as involved in the pathogenesis of human obesity (Krude et al.
Nillni said he suspected that the problem might lie in the brain cells' mechanism for processing the POMC protein to make alpha-MSH.
Further research into the mechanism of ectopic POMC expression may provide a novel target for the treatment of patients with the EAS.
s Norokinin A Duyusal sinirler Keratinositlerde NGF POMC Melanosit, mast h, reseptorlerinde art?
The most important in the melanocortin pathway is the ARCPVN axis where POMC neurons coexpress [alpha]-MSH and cocaine- and amphetamine-regulating transcript (CART), which in turn act upon PVN to curb appetite (Kalra et al.
In rat and human corticotroph adenoma cell series, troglitazone and rosiglitazone decreased the tumor cell growth, increased the apoptosis and lowered the ACTH secretion by inhibiting POMC mRNA expression (16).
Though, when pressed, Tony the singer from POMC compared himself and his band to another Boro centre back, Robert Huth, "as we're both young lads bringing an old school style to a modern audience.
Moreover, in vivo studies found that acute ethanol administration to rodents increased the POMC content of the pituitary, the release of pituitary and hypothalamic [beta]-endorphin, and [beta]-endorphin levels in the blood (Gianoulakis 1993; Modesto-Lowe and Fritz 2005).
Some genes (including the ZNF639 and POMC genes) contain MIR inserts that have been found in all mammals tested including the egg-laying platypus.
However, the effects of SPS or Topiramate on pituitary gene expression are not known; in the present paper, we examine the effects of SPS and Topiramate on mRNAs for GR, CRH-R1, or POMC (involved with production of ACTH).
The first compelling evidence that the POMC gene is involved in the control of human appetite came from a report of 2 defects in ACTH synthesis and in POMC gene translation in 2 children affected by hyperphagia and uncontrolled obesity (5).