Vibration excites Pacinian
corpuscles, and these receptors convey their information through gracile and cuneate fascicles to higher centers.
Researchers found that mice lacking the proper version of a protein called c-Maf have deformed Pacinian
corpuscles, the vibration detectors that surround mouse bones (normal corpuscles shown here ill a mouse's leg).
When you stroke your fingers over a surface, its structure triggers high-frequency vibrations in the finger, to which specific touch receptors, the Pacinian
corpuscles and Merkel disk receptors respond to vibration and light touch (or pressure) , this result may suggest that the distribution of these two kinds of receptors is denser on the ventral forearm.
11) One tumor demonstrated an association with clusters of Pacinian
corpuscles with an S100 protein stain showing tumor cells in the outer layers of the corpuscles (Figure 3, c and d).
It's that feel of a switch going on and off that most people are looking for," said Mike Levin, an executive with haptics startup Pacinian
The response is quite similar to the signal variation of the Pacinian
corpuscle sensory receptor in the dermis and the output is characterized by the temporal differential property.
The tip of the trunk contains two kinds pressure-sensitive nerve endings Meissner's corpuscles that detect infrasonic vibrations, and Pacinian
corpuscles that respond to vibrations with slightly higher frequencies.
The specific ligamentous sensory receptors found at the ankle joint are Ruffini endings and Pacinian
corpuscles (Johansson et al 1991, Michelson and Hutchins 1995).
Deeper sensibility in the fingers is supplied by a rich nerve plexus in which, among many nerve endings, are >800 of the estimated 2000 Pacinian
corpuscles in the whole body.
Similarly, reduced density of Pacinian
corpuscles with aging is responsible for the decline in vibrotactile sensitivities of older adults .
Specialized sensors called Pacinian
fibers, the tips of nerve fibers, detect only a select few of the vibrations--those right around 250 hertz--before sending the signal to the brain.