Paget's disease


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Pag·et's disease

 (păj′ĭts) or Pag·et disease (-ĭt)
n.
1. A disease, occurring chiefly in old age, in which the bones become enlarged and weakened, often resulting in fracture or deformation. Also called Paget's disease of bone.
2. A rare form of breast cancer involving the areola and nipple and usually associated with underlying ductal carcinoma. Also called Paget's disease of the breast, Paget's disease of the nipple.

[After Sir James Paget.]

Paget's disease

(ˈpædʒɪts)
n
1. (Pathology) Also called: osteitis deformans a chronic disease of the bones characterized by inflammation and deformation
2. (Pathology) Also called: Paget's cancer cancer of the nipple and surrounding tissue
[C19: named after Sir James Paget (1814–99), British surgeon and pathologist, who described these diseases]

Pag′et's disease`

(ˈpædʒ ɪts)

n.
1. a disease characterized by episodic accelerated bone resorption and growth of abnormal replacement bone.
2. an inflammatory condition of the nipple associated with breast cancer.
[1875–80; after James Paget (1814–99), English surgeon]

Paget's disease

A disease that involves the abnormal formation and resorption of bone. Bones become soft, weak, thickened, and deformed.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Paget's disease - a disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain and fractures and skeletal deformities
osteitis - inflammation of a bone as a consequence of infection or trauma or degeneration
References in periodicals archive ?
2 and BerEP4 positivity in pagetoid squamous cell carcinoma in situ (pagetoid Bowen's disease) of the perianal region: A mimic of extramammary Paget's disease.
This ruled out a pagetoid spread of melanoma and confirmed a diagnosis of Paget's disease (PD) of the breast.
This provides differentiation from additional entities that typically include giant cells: cherubism, central giant cell granuloma, giant cell tumor in the setting of paget's disease, and aneurysmal bone cyst.
The use of placental ssue in different forms to address the typical effects of bone diseases including arthritis, osteoporosis, bone tumors, Paget's Disease, and alveolar bone degradation.
The use of placental tissue in different forms to address the typical effects of bone diseases including arthritis, osteoporosis, bone tumors, Paget's Disease, and alveolar bone degradation.
M2 EQUITYBITES-June 5, 2017-Mylan introduces generic Reclast Injection for treating Paget's disease
M2 PHARMA-June 5, 2017-Mylan introduces generic Reclast Injection for treating Paget's disease
Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for this product, which is indicated for the treatment of Paget's disease of bone in men and women.
A diagnosis of monostotic Paget's disease was made which satisfactorily responded to single-dose zoledronic acid treatment.
Paget's disease of the bone is a chronic disorder characterized by excessive bone formation and disorganized remodeling.
Paget's disease starts with the purposeless proliferation of osteoclasts that destroy bone, thus releasing minerals from the collagenous matrix.