Parkinson's disease


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Related to Parkinson's disease: Alzheimer's disease, dopamine

Par·kin·son's disease

 (pär′kĭn-sənz) also Par·kin·son disease (-sən)
n.
A progressive disease of the central nervous system, associated with the destruction of brain cells that produce dopamine and characterized by muscle tremors, muscle rigidity or stiffness, abnormally slow movement, and impaired balance and coordination. It usually affects people over the age of 50. Also called paralysis agitans.

[After James Parkinson (1755-1824), British physician.]

Parkinson's disease

(ˈpɑːkɪnsənz)
n
(Pathology) a progressive chronic disorder of the central nervous system characterized by impaired muscular coordination and tremor. Often shortened to: Parkinson's Also called: Parkinsonism, Parkinson's syndrome, paralysis agitans or shaking palsy
[C19: named after James Parkinson (1755–1824), British surgeon, who first described it]

Par′kin•son's disease`

(ˈpɑr kɪn səns)
n.
a neurologic disease believed to be caused by deterioration of the brain cells that produce dopamine, occurring primarily after the age of 60, and characterized by tremors, esp. of the fingers and hands, muscle rigidity, and a shuffling gait. Also called par′kin•son•ism (-səˌnɪz əm)
[1870–75; after James Parkinson (1755–1824), English physician who first described it]

Par·kin·son's disease

(pär′kĭn-sənz)
A disease of the brain, usually in older people, that tends to become more severe over time. Symptoms include shaking, slowed movement, and rigid muscles.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Parkinson's disease - a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination
tremor - shaking or trembling (usually resulting from weakness or stress or disease)
degenerative disorder - condition leading to progressive loss of function
brain disease, brain disorder, encephalopathy - any disorder or disease of the brain
Translations

Parkinson's disease

[ˈpɑːkɪnsənzdɪˌziːz] Nenfermedad f de Parkinson

Parkinson's disease

n. enfermedad de Parkinson, atrofia o degeneración de los nervios cerebrales que se manifiesta con temblores, debilidad muscular progresiva, cambios en el habla, la manera de andar y la postura.
References in periodicals archive ?
Some nurses are aware of the secondary motor manifestations: dysarthria, dysphagia, hypophonia, micrographia, and the mask-like expression seen in some patients with Parkinson's disease.
Speakers also emphasized that millions of Parkinson's patients in Africa, Asia, South America and other underdeveloped countries are not able to buy their medications, walkers or canes; hence they suffer with multiple Parkinson's disease complications including falls.
Job Exposure Matrix (JEM)-Derived Estimates of Lifetime Occupational Pesticide Exposure and the Risk of Parkinson's disease.
In this article, I will be talking about the causes and symptoms of Parkinson's disease in addition to highlighting who is at risk of developing it.
Studying a pair of identical (monozygotic) twins, one affected and one unaffected with Parkinson's disease, another unrelated Parkinson's patient, and four healthy control subjects, the scientists were able to observe key features of the disease in the laboratory.
In this study, a set of identical twins, both with a GBA mutation, provided a unique opportunity to evaluate and dissect the genetic and nongenetic contributions to the development of Parkinson's disease in one twin, and the lack of disease in the other.
DNA mutations resulting in the production of a specific enzyme called glucocerebrosidase (GBA) have been linked to a five-fold greater risk of developing Parkinson's disease; however, only 30% of individuals with this mutation have been shown to develop Parkinson's disease by the age of 80.
It has been known for some time that hippocampal atrophy, for example, is a common feature of Parkinson's disease with dementia.
A team led by Gunther Deuschl, a neurologist at Christian Albrechts University in Kiel, Germany, randomly assigned 152 patients with Parkinson's disease to get surgery or to continue their medication.
TH is a marker for a dopaminergic stem cell phenotype, this cell type being deficient in patients suffering from Parkinson's disease.
Parkinson's disease (PD) is an idiopathic disease of the nervous system characterized clinically by parkinsonism: chronic progressive tremor, bradykinesia, rigidity, and postural instability.
Deep Brain Stimulation, a surgical procedure, is sometimes used to help reduce the symptoms of Parkinson's disease (PD).

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