Researchers have shown that arsenic trioxide prevents the loss of virions from the perinuclear
cell region, leading to an increase in cellular vector genome retention (Mitchell et al.
These regions were masked with the expressing cells image to extract the expressing perinuclear
and peri-plasma membrane regions.
5 SSB (La) Negative CCP Ab IgG Negative Jo-1 Ab Negative Myeloperoxidase Ab Negative Histone Ab IgG Negative pANCA, cANCA IgG Negative HIV screening Negative Hepatitis serology Negative ANA Negative Anti-dsDNA Negative Ab indicates antibody; ANA, antinuclear antibody; anti-dsDNA, anti- double-stranded DNA antibody; cANCA, cytoplasmic antineutrophil cytoplasmic antibody; BUN, blood urea nitrogen; CCP, cyclic citrullinated peptide; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; GFR, glomerular filtration rate; Ig, immunoglobulin; pANCA, perinuclear
antineutrophil cytoplasmic antibodies; RNP, ribonucleoprotein.
elegans, cell differentiation is accompanied by a cell-type specific 3D re-organization of the nucleus, leading to the internal localization of active tissue-specific promoters and the perinuclear
sequestration of repressed tissue-specific promoters.
clearing was evident in cell block section (Figure 2a).
Consequently, the essential parameters allowing evaluating the red cell capability under the adaptation conditions are the perinuclear
space characteristics, primarily, the width and depth.
Merkel cell carcinoma reacts positively for neuroendocrine markers such as synaptophysin and chromogranin, showing a characteristic perinuclear
dot-like staining pattern with pan-cytokeratin and CK20 immunohistochemistry (figure 2).
The neoplasms were predominantly composed of small-to-medium lymphoid cells with slightly irregular nuclear contours, and plasma cells with characteristic cartwheel nuclei and perinuclear
halos were scattered (Fig.
Some of the keratinocytes showed larger electron lucid vacuoles that were arranged in a perinuclear
position and these vacuoles appeared to develop from the progressive degeneration of the mitochondria.
The cytomorphologic features of infection with Trichomonas vaginalis, historically described as including inflammatory cannonball'' squamous cells with perinuclear
halos, reactive nuclear changes, and attachment of Trichomonas organisms to squamous cells, are well recognized in LBP tests.
A patient with perinuclear
anticytoplasmic antibody (p- ANCA) and a pulmonary renal vasculitic syndrome almost always has MPA rather than Wegener's granulomatosis (WG) (1,2).
Antibodies to perinuclear
factor (APF), keratin (AKA) and filaggrin were more specific to RA.