phlebotomus fever

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phle·bot·o·mus fever

 (flĭ-bŏt′ə-məs)
[New Latin Phlebotomus, sand fly genus (from Late Latin phlebotomus, lancet, from Greek phlebotomos, opening a vein; see phlebotomy).]
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Comprehensive molecular detection of tick-borne phleboviruses leads to the retrospective identification of taxonomically unassigned bunyaviruses and the discovery of a novel member of the genus phlebovirus.
Phleboviruses (family Bunyaviridae, genus Phlebovirus) are negative-sense tri-segmented RNA viruses for which mosquitoes, ticks, and sand flies are vectors.
Several species of Leishmania and phleboviruses have a common Phlebotomus spp vector.
Inhibition of bunyaviruses, phleboviruses, and hantaviruses by human MxA protein.
Sequence analysis showed a high genetic diversity with recognized phleboviruses, suggesting that this virus could represent a new species within the Phlebovirus genus.
The Gorgas Memorial Institute in Panama City tested dengue -negative samples from this outbreak for alphaviruses, flaviviruses, and phleboviruses and detected Punta Toro virus species complex (PTVs) in some samples.
With the recent discovery of SFTSV, HRTV, and other novel phleboviral agents in recent years (12-14), it is apparent that tickborne phleboviruses have been largely underrecognized as potential human disease agents.
Orthobunyaviruses and phleboviruses are transmitted to animals and humans by blood-feeding arthropods such as mosquitoes, sandflies, and ticks (1,2).
Consequently, phleboviruses similar to ABIV may be present in bird populations in the southern areas of Africa and South America.
Comparative neutralization tests with related viruses were not performed, because we had previously found that murine antiserum developed against the other known phleboviruses in the United States--Sunday Canyon virus (7), Rio Grande virus (8), and Lone Star virus (9)--had no appreciable neutralizing activity against HRTV (Table 2).
Results of routine microbiologic examinations for bacteria by culture and antigen detection were negative in all cases, as were serologic and genetic tests for hantaviruses, phleboviruses, and Rickettsiales bacteria, performed as described (10).