plasma cell

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Related to Plasma cells: Macrophages, Histiocytes, Memory cells

plasma cell

n.
Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, and lymph nodes. Also called plasmacyte.

plas′ma cell`


n.
an antibody-secreting cell, derived from B cells, that plays a major role in antibody-mediated immunity. Also called plas•ma•cyte (ˈplæz məˌsaɪt)
[1885–90]

plasma cell

A cell that produces antibodies as part of an immune response. B cells develop into plasma cells. See Note at antibody.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasma cell - a cell that develops from a B lymphocyte in reaction to a specific antigenplasma cell - a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood
lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection
plasmablast - the precursor of a plasma cell
References in periodicals archive ?
Most medical problems related to multiple myeloma are caused by the build-up of abnormal plasma cells in the bone marrow and the presence of paraprotein in the blood or in the urine.
Multiple myeloma is a form of blood cancer that arises from plasma cells, a type of white blood cell, found in bone marrow.
These discoveries, published in two prestigious journals PNAS and Nature Communications, advance the understanding of plasma cells and the antibody response, and may lead to optimisation of vaccine development and improved treatment for patients with autoimmune diseases such as lupus and tumours such as multiple myeloma[1].
In addition, the surrounding lymphoid tissue showed against the background of what appeared to be preceding follicular hyperplasia features of marked folliculolysis, and increased plasmacytoid cells and plasma cells were also seen populating some of the follicles.
A 68-year-old woman with a bone marrow biopsy positive for kappa monotypic plasma cells (approximately 90% total) and flow cytometric analysis showing kappa-restricted plasma cells (approximately 17% of total) had unremarkable serum and urine immunofixation electrophoresis (Fig.
The Plasma Cell Screening Tube (PCST) can be used to help discriminate between aberrant and clonal plasma cells.
Plasma cells are polyclonal and predominantly of the IgG4 subtype, the rarest class of immunoglobulin.
The plasma cell type is distinguished by the presence of larger lymphoreticular nodules separated by sheets of plasma cells and by a less vascular stroma.
Abnormal plasma cells secrete abnormal immunoglobulins that can be detected monoclonally (M peak) in serum and/or urine via electrophoresis.
PLASMA cell leukaemia is a rare cancer involving a subtype of white blood cells called plasma cells.
Tokyo, Apr 22, 2011 - (JCN Newswire) - An article in Science Signaling by researchers at the RIKEN Research Center for Allergy and Immunology (RCAI) has clarified for the first time the mechanism governing differentiation of B cells into antibody-producing plasma cells.
According to the company, the robotic plasma cells provide customers with "an exceptional package that is functional and is easy to integrate into new or existing production facilities.

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