dendritic cell

(redirected from Plasmacytoid dendritic cells)
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dendritic cell

n.
Any of various white blood cells that have long projections from the cell body and function in the immune response by taking in and processing antigens and presenting them to T cells in lymph nodes, thus activating the T cells. Immature dendritic cells are found chiefly in skin and mucosal surfaces.
Translations
célula dendrítica
cellula dendritica
References in periodicals archive ?
Xu et al (25) also reported that HBsAg can suppress TLR9 transcription in plasmacytoid dendritic cells.
Food and Drug Administration (FDA) for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare and aggressive hematologic malignancy for which there is no effective treatment.
Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization.
Circulating, interferon-producing plasmacytoid dendritic cells decline during human aging.
Immunohistochemistry for CD123 demonstrated an increased number of plasmacytoid dendritic cells (Figure 1).
His laboratory also discovered the human plasmacytoid dendritic cells (pDCs), a novel cell type in the immune system that is specialized in anti-viral immune responses and implicated in the development of autoimmune diseases.
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.
Then they detail such techniques as genomic DNA affinity chromatography to isolate interferon-inducible DNA binding factors, an inteferon-based cancer vaccine protocol applied to several types of murine cancers, and flow cytometric techniques to study plasmacytoid dendritic cells in mixed populations.
The title of his abstract is "A novel class of host-derived etiological agent for autoimmunity: oligomers of endogenous proteins complex with self-nucleic acids and trigger Type I interferon production by plasmacytoid dendritic cells.
The plasmacytoid dendritic cells, although hardly recognized when present singly, tend to cluster, particularly at the margins of the necrotic foci (Figure 1, B).