(redirected from Plasmids)
Also found in: Thesaurus, Medical, Encyclopedia.
Related to Plasmids: Restriction enzymes


A circular, double-stranded unit of DNA that replicates within a cell independently of the chromosomal DNA. Plasmids are most often found in bacteria and are used in recombinant DNA research to transfer genes between cells.


(Genetics) a small circle of bacterial DNA that is independent of the main bacterial chromosome. Plasmids often contain genes for drug resistances and can be transmitted between bacteria of the same and different species: used in genetic engineering
[C20: from plasm + -id1]


(ˈplæz mɪd)

a strand or loop of DNA that exists independently of the chromosome in bacteria and yeast and that is capable of genetic replication: used in recombinant DNA procedures as a vehicle of gene transfer.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasmid - a small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication
cellular inclusion, inclusion body, inclusion - any small intracellular body found within another (characteristic of certain diseases); "an inclusion in the cytoplasm of the cell"
References in periodicals archive ?
Plasmids are small, circular, double-stranded molecules of DNA found in bacteria and yeast.
It also acts as a strong DNA-intercalating agent and biotechnologists use it widely as a potent plasmid curing agent wherein a bacterium is made free of plasmids.
Since then, mcr-1 has been identified on plasmids of various incompatibility (Inc) types associated with 0, 1, or 2 copies of the insertion sequence (IS) ISApl1 (2), and it has been identified in other species (most notably Salmonella spp.
If only one or a few plasmids are inserted into the cell, the new DNA could just be silenced.
coli and Salmonella plasmids carrying gene (blaCMY-2) encodes an AmpC-type beta-lactamase that hydrolyzes third-generation cephalosporins and represent share a common ancestor with the Yersinia and Photobacterium plasmids [8].
AAV manufacturing has traditionally required unique custom batches of helper plasmids.
The protein coding regions in the plasmids used for transformation were sequenced to confirm no PCR errors.
Plasmids from wild-type isolates were extracted by using a Qiagen Plasmid Midi kit (Qiagen, Germany).
coli HB101 (plasmid less and sensitive to antibiotics) were transformed with different individually isolated plasmids.
Upon successful construction, the plasmid was transformed into bacteria to produce more plasmids.
Scientists in a wide range of biomedical disciplines survey the status of new plasmids that have emerged in the development of non-viral vectors for gene and cell therapy and DNA vaccination.