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Plumbagin

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Plum`ba´gin    (plŭm`bā´jĭn)
n.1.(Chem.) A crystalline substance said to be found in the root of a certain plant of the Leadwort (Plumbago) family.
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The only active naphthoquinone, plumbagin is an antiprotozoal compound with activity against Leishmania anzazorzensis and Leishmania doizovani in vitro and in vivo (Croft 1985; Fournet 1992) and antibacterial and antifungal activities (Gujar 1990).
Antimicrobial properties of Lawsonia inermis (henna): a review by Habbal, O.A.; Al-Jabri, A.A.; El-Hag, A.G. / Australian Journal of Medical Herbalism
Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats.
Benzobijuglone, a novel cytotoxic compound from Juglans mandshurica, ... by Li, Zhi-Bo; Wang, Jing-Yun; Jiang, Bo; Zhang, Xiu-Li; An, Li-Jia; Bao, Yong-Ming / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
tuberculosis, exhibited increased susceptibility to INH when combined with plumbagin (2-methyljuglone), another naphthoquinone with similar structure, indicating synergistic activity.
Activity of 7-methyljuglone in combination with antituberculous drugs ... by Bapela, N.B.; Lall, N.; Fourie, P.B.; Franzblau, S.G.; Van Rensburg, C.E.J. / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
 
 
 
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