Plumbagin


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Plum`ba´gin

    (plŭm`bā´jĭn)
n.1.(Chem.) A crystalline substance said to be found in the root of a certain plant of the Leadwort (Plumbago) family.
References in periodicals archive ?
Antidiabetic effect of plumbagin isolated from Plumbago zeylanica L root and its effect on GLLTT4 translocation in streptozotocin-induced diabetic rats.
Plumbagin (2-methoxy-5-hydroxy-1,4-naphthoquinone) is a natural naphthoquinone possessing various pharmacological activities such as antimalarial (16), antimicrobial (17), anticancer (18), cardiotonic (19) and antifertility action (20).
Antimicrobial activity of disiquinone and plumbagin for the root of Diospyru mespiliformis.
Plumbagin, 5-hydroxy-2-methyl-1, 4-nepthoquinone isolated from Plumbago zeylanica cured R-plasmids in E.
The only active naphthoquinone, plumbagin is an antiprotozoal compound with activity against Leishmania anzazorzensis and Leishmania doizovani in vitro and in vivo (Croft 1985; Fournet 1992) and antibacterial and antifungal activities (Gujar 1990).
The presence of some plant polyphenols such as piceatannol, taxifolin, coumestrol, plumbagin, (-)-gallochatechin, (-)-rhein, (-)-epigallocatechin gallate, (-)-gallocatechin gallate, and (-)-epacatechin also decreased the number of revertants.
They evaluated germination and growth of alfalfa (Medicago sativa), annual ryegrass (Lolium multiflorum), and velvetleaf (Abutilon theophrasti) against known allelochemicals such as cinmethylin, coumarin, plumbagin, nigericin, juglone, and trans-cinnamaldehyde.
1,4-Naphthoquinone derivatives such as plumbagin and shikonin are one such group of phytochemicals that have strong anticancer and anti-metastatic activities (Lu et al.
Dose dependent reversal effects of plumbagin on metabolism of arachidonic acid in porcine polymorphonuclear leukocytes.
2013) have suggested these mechanisms work as an action route of 5-hydroxy-2-methyl-1,4-naphthoquinone, known as plumbagin, against S.
mexicana Hederin Hederacolchiside A1 Pentamidine Ampho B Maesa balansae Maesabalides III Maesabalides L infantum (Myrsinaceae) IV Amphotericin B L infantum Stibogluconate Stibogluconate L donovani Pera benensis Plumbagin L amazonensis 3,3' - Biplumbagin 8,8'- Biplumbagin Glucantime Cephaelis 1- L.
Plumbagin induces G2-M arrest and autophagy by inhibiting die AKT/ mammalian target of rapamycin pathway in breast cancer cells.