(redirected from Polymerases)
Also found in: Thesaurus, Medical, Encyclopedia.


 (pə-lĭm′ə-rās′, -rāz′, pŏl′ə-mə-)
Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of polynucleotides of DNA or RNA using an existing strand of DNA or RNA as a template.


(Biochemistry) any enzyme that catalyses the synthesis of a polymer, esp the synthesis of DNA or RNA


(ˈpɒl ə məˌreɪs, -ˌreɪz)

any of several enzymes that catalyze the formation of a long-chain molecule by linking smaller molecular units.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.polymerase - an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
DNA polymerase - the enzyme responsible for DNA replication
RNA polymerase, transcriptase - the enzyme that copies DNA into RNA
reverse transcriptase - a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses
References in periodicals archive ?
The enzymes segment is divided into the ligases, phosphatases, polymerases, proteases and proteinases, restriction endonucleases, reverse transcriptases, and other enzymes sub-segments.
The polymerase sub-segments are high-fidelity DNA polymerase, T4 DNA polymerase, Taq DNA polymerase, and other polymerases.
Agilent's molecular biology solutions include PCR instrumentation, high fidelity polymerases, and specialty enzymes, along with qPCR instrumentation and reagents, and market leading mutagenesis and cloning products.
Within the context of a living cell, DNA replication by polymerases also initiates from primer sequences, but without either of these methods.
Several methods have been developed to measure the activity of DNA polymerases, but complexity, time requirements, and specialized instrumentation have prevented their widespread use.
The sliding clamp then serves to anchor special enzymes called polymerases to the DNA, ensuring efficient copying of the genetic material.
6) Automation of PCR along with the use of Taq polymerase and other heat stable polymerases, opened the door for various modifications of the technique including the development of real-time PCR assays, reverse transcription PCR (RT-PCR), multiplex PCR, and nested PCR all commonly used in clinical laboratories, forensic laboratories, and research facilities.
The invention also provides thermostable polymerases and nucleic acids encoding thermostable polymerases having altered fidelity, for example, high fidelity polymerases and low fidelity polymerases.
The genes in these blocks code for the 1918 flu's polymerases, which are proteins crucial for a virus' replication in animal hosts.
Woodgate's laboratory recently discovered and purified polymerase iota (pol [Iota], one of a superfamily of DNA polymerases that synthesize short stretches of DNA and are relatively inaccurate--that is, they may allow the A, C, G, or T base moieties to be matched to an incorrect mate (for instance, matching G with T or A, rather than with its proper mate, C).
The DNA polymerases contained in Kapa Biosystems' reagents have been engineered through a process of molecular evolution and possess unique amino acid modifications that confer dramatic improvements to the function of the enzymes.
It remains to raise the temperature to one more conducive to enzyme activity, 72[degrees]C, (extension; D) and allow the polymerases to act on their substrates, extending the 3' end of each primer in a template-directed fashion toward the opposing primer's sequence.

Full browser ?