In research published today in the journal Nature Communications, a team of scientists led by Dr Taylor Schmitz and Professor Anderson used a task known as the 'Think/No-Think' procedure to identify a significant new brain process that enables the prefrontal cortex
to successfully inhibit our thoughts.
8,14] The areas of interest included: the left dorsolateral prefrontal cortex
(IDLPFC), ventromedial prefrontal cortex
, and anterior cingulate cortex.
The prefrontal cortex
is vital in decision making, impulse control, risk management, logical thinking, organized thinking, personal development, attention and complex planning among others.
In the study, first author Brad Rocco, a graduate student in Fishs laboratory, and colleagues compared GABA synthesizing and packaging proteins within chandelier cell cartridges, as well as the density of these cartridges in the prefrontal cortex
of 20 schizophrenia subjects and 20 comparison subjects.
We know that damage to the prefrontal cortex
causes working memory deficits (along with many other changes).
Each medial prefrontal cortex
was excised, processed routinely and stained with the haematoxylin and eosin, and cresyl fast violet stains.
Given the strong linkage between the prefrontal cortex
and various psychiatric illness, he said the study opens the possibility of identifying and targeting different cell types with diverse therapeutic approaches, including drugs or external stimulation techniques.
Walking along the highway did nothing to diminish activity in the subgenual prefrontal cortex
The precise mechanism by which ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, improves treatment-resistant depression has not been identified, though the prefrontal cortex
is thought to play a role in modulating depression.
Results showed that in lean adolescents, glucose ingestion increased cerebral blood flow in the striatum, insula, anterior cingulate cortex and the prefrontal cortex
, all of which are regions of the brain that reside in the cortico striatal-limbic circuitry undergoing significant developmental changes during adolescence, said Dr.
2009) suggested that the behaviors inherent in psychopaths represent a disruption of the integrated functioning of the prefrontal cortex
and areas of the limbic system.
This control of fear behaviour is based on the activation of neurons in the prefrontal cortex
that are in contact with specific areas of the amygdala.