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prodrug
(redirected from Prodrugs)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
pro·drug  (prdrg)
n.
An inactive precursor of a drug, converted into its active form in the body by normal metabolic processes.

prodrug [ˈprəʊˌdrʌg]
n
(Life Sciences & Allied Applications / Biochemistry) a compound that is itself biologically inactive but is metabolized in the body to produce an active therapeutic drug


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Prodrugs, which have been used extensively in pharmaceutical development to optimize delivery of an active drug or to minimize toxicity, are pharmacologically inactive precursors to an active drug that requires metabolism for activation.
Indianapolis, IN), an emerging leader in small molecule cancer therapies addressing critical cell signaling pathways, announced that the United States Patent and Trademark Office has issued PI-3 kinase inhibitor prodrugs, United States Patent No.
The therapy, known as Adept, uses the ability of an enzyme to turn other- wise harmless mole- cules, or prodrugs, into cell-killing drugs.
 
 
 
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