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protease inhibitor

   Also found in: Medical, Legal, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
protease inhibitor
n.
An anti-HIV drug that blocks the action of the enzyme protease, which is needed for viral replication.

protease inhibitor
n
(Medicine / Pharmacology) any one of a class of antiviral drugs that impair the growth and replication of HIV by inhibiting the action of protease produced by the virus: used in the treatment of AIDS
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.protease inhibitor - an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs
antiviral, antiviral agent, antiviral drug - any drug that destroys viruses
drug cocktail, HAART, highly active antiretroviral therapy - a combination of protease inhibitors taken with reverse transcriptase inhibitors; used in treating AIDS and HIV
Crixivan, indinavir - a protease inhibitor (trade name Crixivan) used for treating HIV
nelfinavir, Viracept - a protease inhibitor (trade name Viracept) used in treating HIV usually in combination with other drugs
Norvir, ritonavir - a protease inhibitor (trade name Norvir) used in treating HIV
Invirase, saquinavir - a weak protease inhibitor (trade name Invirase) used in treating HIV


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The team then used a specific small-molecule protease inhibitor of calpain in these mice.
95 Hardcover QP551 Lundblad brings together solution protein chemistry and proteomic technology to describe the chemical modification of proteins, the application of site-specific chemical modification to proteomics, protease inhibitors in sample preparation, and prefractionation.
The anti-HIV drug "cocktail" had begun changing the face of the AIDS epidemic a year after the introduction of protease inhibitors, The Advocate reported in late 1996.
 
 
 
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