protein kinase

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Related to Protein kinase c-alpha: Protein kinase B

protein kinase

n.
Any of a group of kinases that phosphorylate the amino acids serine, threonine, and tyrosine in certain proteins, that regulate essential aspects of cell growth and movement, and that can cause cancer and other diseases when dysfunctional.
References in periodicals archive ?
The Company's lead compound, GLI005, is a selective inhibitor of an important signaling molecule called Protein Kinase C-alpha (PKC-alpha), found in abnormally high levels in many types of cancer.
Specifically, Affinitac is a selective inhibitor of protein kinase C-alpha (PKC-alpha) expression.
The licensed compound, ISIS 3521, is a selective inhibitor of protein kinase C-alpha (PKC-alpha) expression and is in early Phase III trials for the treatment of non-small cell lung cancer.
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