tyrosine kinase inhibitor

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Related to Protein kinase inhibitor: Gleevec, Sorafenib, Sunitinib, Jakafi, Votrient

tyrosine kinase inhibitor

n.
Any of a class of drugs, such as imatinib, that target and block the action of specific tyrosine kinases and are used especially in the treatment of chronic myelogenous leukemia and other cancers.
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Noun1.tyrosine kinase inhibitor - a drug used in cases of chronic myeloid leukemia
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
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Contract notice:Medications monoclonal antibodies (l01xc) and protein kinase inhibitor medications (l01xe)
Other reported skin reactions seen in conjunction with protein kinase inhibitor therapy include skin rashes, pruritus, blistering, peeling skin, hand-foot skin reaction, and difficulties with wound healing.
According to Daniel Levitt, CytRx chief medical officer, the company is optimistic that its dual protein kinase inhibitor bafetinib will demonstrate efficacy in patients with high-risk B-CLL who have failed other therapies and have few viable treatment options.
The effects are reproduced by 8-bromo-guanosine 3',5'-cyclic monophosphate and suppressed in the presence of the cGMP-dependent protein kinase inhibitor KT-5823.
Archexin is being developed as an Akt protein kinase inhibitor with potential utility to inhibit cancer cell survival and proliferation, angiogenesis and drug resistance.
The protein kinase inhibitor has the highest number of molecules under development, accounting for 42% of the oncology pipeline, with 194 monoclonal antibody molecules in development and 63 vaccine molecules in various stages of development.
Continuous supply of cytostatic agents with monoclonal antibody - drug Bevacizumab, Trastuzumab and a protein kinase inhibitor Erlotinib hydrochoricum for hospital pharmacies Na Homolce Hospital for 48 months.
Continuous supply of cytostatics with a monoclonal antibody - active ingredient Bevacizumab, Trastuzumab and protein kinase inhibitor Erlotinib hydrochoricum for hospital pharmacies Na Homolce Hospital for 48 months.
As a novel Akt protein kinase inhibitor, Archexin has the potential to develop into an important therapeutic for the treatment of pancreatic cancer, a disease with a low survival rate and limited treatment options.
The company uses its patented RightSize technology in combination with well-documented substances for the development of improved and generic versions of marketed cancer drugs, primarily protein kinase inhibitors (PKIs).
Grant's research group provides the primary in vitro pharmacology support for preclinical cancer research projects including drug discovery efforts on protein kinase inhibitors.
Denning said a class of drugs called protein kinase inhibitors potentially could shrink tumors by turning the PKC gene back on.

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