To test that idea, Fahy and his group exposed mucus samples taken from CF patients to two current CF medications: Pulmozyme
, a drug that breaks up DNA polymers, and N-acetylcysteine (NAC), which targets disulfide bonds between mucin polymers.
26, 2015 /PRNewswire/ -- The eRapid Nebulizer System (eRapid) from PARI has been approved as the first electronic nebulizer by the Food and Drug Administration to deliver Genentech's Pulmozyme
for cystic fibrosis treatment.
The Swiss drugmaker already markets Pulmozyme
for cystic fibrosis and Xolair for severe asthma in the United States, and has other experimental respiratory products in clinical development, including another severe asthma drug called lebrikizumab.
The 1990s saw the introduction of the drug Pulmozyme
to improve clearance of bronchial secretions (7).
5 mg of Pulmozyme
once a day, or 321 patients with 2.
But he has been great since he went on a new inhaler drug called Pulmozyme
which helps break down the mucus in his lungs.
Kirk Raab, Genentech's CEO, is more direct: "I don't think we would have developed Pulmozyme
if the Clinton price controls had been imposed.
The cost of these drugs is generally quite high; for example, Pulmozyme
, for the treatment of cystic fibrosis, is approximately $10,000 per year.
Products of the company are marketed under various brand names such as Activase, Avastin, Cathflo Activase, Rituxan, Xolair, Tarceva, Pulmozyme
, Genentech, Herceptin, Lucentis, Raptiva, TNKase and Nutropin among others.
Roche markets Pulmozyme
and Xolair in the US and has other novel therapeutic medicines targeting respiratory diseases in clinical development.
She has led the alliance management function for numerous global strategic alliances, and has contributed to the approval and commercialization of several biologics, including Rituxan, Zevalin, Pulmozyme
, and Activase.
MEDICATIONS: Mabthera, ROACTEMRA, Valcyte, Pulmozyme