Purkinje cell

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Related to Purkinje cell: nerve cell, Purkinje cell layer

Pur·kin·je cell

A large, drop-shaped, densely branching neuron that is the characteristic cell of the cerebellar cortex.

[After Johannes Evangelista von Purkinje (1787-1869), Bohemian physiologist.]

Pur•kin′je cell`

(pərˈkɪn dʒi)
a large, densely branching neuron in the cerebellar cortex of the brain.
[1885–90; see Purkinje fiber]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Purkinje cell - a large densely branching neuron that is the characteristic cell of the cerebellar cortex
brain cell - a nerve cell in the brain
References in periodicals archive ?
Although zinc supplementation in one study did not mitigate alcohol-induced cerebellar Purkinje cell loss following developmental alcohol exposure (Chen et al.
Effect of prenatal exposure to diclofenac sodium on Purkinje cell numbers in rat cerebellum: A stereological study.
Another interesting pattern in the cerebellum was seen for MABs 12C4 (J), 12D11 (K), and 7E6 (L), wherein the wide, sinusoidal-shaped area containing the Purkinje cell layer was particularly obvious because of the lack of any reaction product.
Variations in the human Purkinje cell population according to age and sex.
At P5 and P7, Calbindin immunostaining showed formation of the Purkinje cell layer with extension of the dendrites and axons (Fig.
For example, Purkinje cell apoptosis is enhanced in utero during fetal alcohol syndrome [35].
The cerebellar folia also had widespread lesions, with a predilection for Purkinje cell necrosis and loss, with characteristic Bergmann glial and microglial proliferation and dendritic spheroids in the overlying layer; however, axonal torpedoes were rarely found (Figure 4).
The Purkinje cell bodies are arranged in a sheet, one cell thick at the interface of the molecular and granular layers.
Thyroid hormone induces cerebellar Purkinje cell dendritic development via the thyroid hormone receptor alpha1.
Roman (2007) hypothesized that even transient intrauterine deficits in thyroid hormones (as little as 3 days) at critical points in gestation could alter the cortical architecture, interfering with neuronal migration and Purkinje cell growth, indications of both of which have been observed in autopsy studies of autism (Fatemi et al.
Investigations using animal models have determined that the rate of acquisition of Pavlovian conditioning is diminished proportionate to cerebellar Purkinje cell loss (Brown et al.