(redirected from Retrotransposition)
Also found in: Thesaurus, Medical, Encyclopedia.
Related to Retrotransposition: Transposons, long interspersed elements


A segment of DNA that is capable of moving into a new position within the same or another chromosome or plasmid. Also called jumping gene.


(Genetics) genetics a genetic element that can move from one site in a chromosome to another site in the same or a different chromosome and thus alter the genetic constitution of the organism
[C20: from transpos(e) + -on]


(trænsˈpoʊ zɒn)

a gene or set of genes capable of inserting copies of itself into other DNA sites within the same cell. Also called jumping gene.
[1974; transpos (ition) + -on1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.transposon - a segment of DNA that can become integrated at many different sites along a chromosome (especially a segment of bacterial DNA that can be translocated as a whole)
deoxyribonucleic acid, desoxyribonucleic acid, DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
References in periodicals archive ?
Because both lack introns, they are probably products of an early retrotransposition event.
Vanadium induces VL30 retrotransposition at an unusually high level: a possible carcinogenesis mechanism.
Having this retrotransposition ability, retrotransposons can induce massive chromosomal rearrangements thus influence an increase, change and functionality of genome shape which have been documented extensively in different type of plant species (Grandbastien, 2015).
LINE-1 retrotransposons comprise approximately 20% of the mammalian genome, and L1 retrotransposition events can create genetic diversity by a variety of mechanisms.
To the standard paradigm of slow accumulation of random point mutations as the major mechanism of biological variation must now be added new data and concepts of symbiosis, gene duplication, horizontal gene transfer, retrotransposition, epigenetic control networks, niche construction, stress-directed mutations, and large-scale reengineering of the genome in response to environmental stimuli.
L1 retrotransposition in human neural progenitor cells," Nature, vol.
LINE-1 retrotransposition events lead to genomic deletions, [sup][1] chromosome breaks and genomic instability.
In addition, there are also several reports that the small imprinted genes that reside in the introns of other genes, such as Mcts2, Nap1l5, Inpp5f_v2, U2af1-rs1 and Nnat, are thought to have been inserted into their present positions by cDNA retrotransposition.
The viroids are evolutionarily escaped archaeal group I introns which have retrotransposition and self splicing qualities.
It is also possible that some important autosomal genes that must persist in double dose in both sexes, impede neo-Y elimination, despite degeneration, or else that during its evolution the neo-Y acquired other autosomal segments (Graves 2005), for example by retrotransposition (Lahn & Page 1999).
SINEs can jump within the genome by a process called retrotransposition in which the retrotransposon "master gene" is copied into an RNA intermediate, reverse transcribed into DNA, and inserted into the genome of its host at a new location (Deininger et al.