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SCID

   Also found in: Medical, Acronyms, Wikipedia 0.01 sec.
SCID
abbr.
severe combined immunodeficiency

SCID
abbreviation for
(Medicine / Pathology) severe combined immune deficiency; a serious condition in which babies are born with reduced numbers of T- and B-lymphocytes, which impairs their immune systems and makes them susceptible to severe infections and cancer
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.SCID - a congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
immunodeficiency - immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
ADA-SCID - SCID resulting from mutation of a gene that codes for adenosine deaminase
X-linked SCID, X-SCID - SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor


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All 10 children who had SCID caused by a lack of adenosine deaminase were still alive a median of four years after the missing enzyme was replaced, Maria-Grazia-Roncarolo, MD, of the San Raffaele Telethon Institute for Gene Therapy in Milan, Italy, and colleagues reported in the January 29 issue of the New England Journal of Medicine (NEJM).
The HRSD, BDI, and SCID mood modules were serially administered throughout the peripartum period to assess depressive symptoms and episodes.
But gene therapy attempts are restricted to SCID patients who have no alternative, after doctors in 2003 discovered a few babies saved by gene therapy went on to develop cancer--again, linked to the virus used to deliver the genes.
 
 
 
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