SCID


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SCID

abbr.
severe combined immunodeficiency

SCID

abbreviation for
(Pathology) severe combined immune deficiency; a serious condition in which babies are born with reduced numbers of T- and B-lymphocytes, which impairs their immune systems and makes them susceptible to severe infections and cancer
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.SCID - a congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life
immunodeficiency - immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
ADA-SCID - SCID resulting from mutation of a gene that codes for adenosine deaminase
X-linked SCID, X-SCID - SCID in male children resulting from mutation of a gene that codes for a protein on the surface of T cells that allows them to develop a growth factor receptor
References in periodicals archive ?
Wisconsin was the first state in the United States to initiate a statewide newborn screening program in 2008 for identifying babies born with SCID or other T cell lymphopenias.
Newborns with SCID typically have zero or low amounts of TREC DNA compared to healthy infants.
SCID is a group of disorders caused by defects in genes involved in the development and function of T cells and other infection-fighting immune cells.
Similarly, the SCID probes cases of corruption involving members of the judiciary and prominent holders of public office.
Before the completion of the contemplated sale, Sony will first transfer certain of its chemical products-related businesses to SCID, while at the same time SCID will transfer its non-chemical related businesses, as well as a portion of SCID's assets, to Sony.
SCID, often called "bubble boy disease", causes a defect in the white blood cells that helps protect the body from viruses, bacteria and fungi.
The feasibility of a screening assay for detection of SCID that is applicable to the newborn sample, the NBS dried blood spot (DBS), has been investigated in a research setting by Chan and Puck (9), who recognized that the Douek assay (10) for quantifying thymic production of T cells [which measures excisional DNA products of T-cell-receptor gene rearrangements (TRECs)] could be used on the NBS DBS to measure the 1 common underlying characteristic of all SCID conditions, the complete absence or extremely low concentration of autologous or functional T cells (1).
The data showed significant agreement in schizophrenia diagnoses between the SCID and experts only.
None of the patients died developed leukemia, which has been a serious side effect in previous gene therapy studies in patients with X-linked SCID.
Logistic regression analysis included the symptoms of auditory hallucinations, Schneiderian first-rank symptoms, and negative symptoms, based on the SCID and coded as present or absent.
When he became seriously ill over the Christmas period in 2003, Colin and Carol, from Marlowe, Bucks, went through an agonising period as he was tested for various serious conditions before it was discovered he had SCID.