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1. (also dōN) Used formerly as a title for male members of Portuguese and Brazilian royalty, aristocracy, and hierarchy, preceding the given name.
2. Roman Catholic Church Used as a title before the names of Benedictine and Carthusian monks in major or minor orders.

[Portuguese, from Latin dominus, lord, master; see dem- in Indo-European roots.]


1. (Roman Catholic Church) (sometimes capital) RC Church a title given to Benedictine, Carthusian, and Cistercian monks and to certain of the canons regular
2. (Historical Terms) (formerly in Portugal and Brazil) a title borne by royalty, princes of the Church, and nobles
[C18 (monastic title): from Latin dominus lord]


abbreviation for
1. (Architecture) Deo Optimo Maximo
2. informal Dirty Old Man
abbreviation for
(Automotive Engineering) Dominican Republic (international car registration)
[(for sense 1) Latin: to God, the best, the Greatest]


(dɒm; for 2 also Port. dɔ̃)

1. (sometimes cap.) a title of a monk in certain monastic orders.
2. (usu. cap.) a Portuguese title affixed to a man's given name; Sir: formerly a title of certain dignitaries.
[1710–20; short for Latin dominus lord, master]


a suffix forming nouns that refer to domain (kingdom), collection of persons (officialdom), rank or station (earldom), or general condition (freedom).
[Middle English; Old English -dōm; c. Old Norse -dōmr, German -tum; see doom]


1. Dominica.
2. Dominican.


1. domain.
2. domestic.
3. dominant.
4. dominion.
References in periodicals archive ?
A newly developed mouse monoclonal SOX10 antibody is a highly sensitive and specific marker for malignant melanoma, including spindle cell and desmoplastic melanomas.
EMT-associated genes (CDH2, COL1A2, COL5A2, FN1, MAP1B, MMP3, SOX10, SPP1, ZEB1, and ZEB2), DNA repair genes (RAD51) (21) or targets relevant for cancer therapy.
Several genes, including RET gene, Endothelin-3 and Endothelin type B receptor, transcription factors such as SOX10, PHOX2B or ZFHX1B are implicated in its pathogenesis.
This complex process is governed by a network of transcription factors, such as PAX3 and SOX10 and mutations in these genes have been associated with developmental syndromes.
They then performed a transcription factor screening assay and found three transcription factors out of those 10 that are required for melanocytes: SOX10, MITF, and PAX3, a combination dubbed SMP3.
The transcription factors SOX9 and SOX10 are vitiligo autoantigens in autoimmune polyendocrine syndrome type I.
Analysis of SOX10 function in neural crest-derived melanocyte development: SOX 10-dependent transcriptional control of dopachrome tautomerase.
Hypomyelination in 22gl3 SOX10 CNS and PNS Sensory polyneu- 1p35.
Immunohistochemically, tumor cells are consistently positive for S100 (Figure 14, B), SOX10, and vimentin, but negative for melanocytic markers HMB-45, Melan-A, tyrosinase, and MITF (microphthalmia transcription factor).
The feather pigmentation related genes including MC1R, TYR, PMEL, MLPH, ASIP, SOX10, and SLC34A2 are well known.
Additional immunomarkers that may be helpful, depending on the differential diagnosis, include CD45 (for lymphoma); S100, HMB-45, MART1, and SOX10 (for melanoma; both S100 and SOX10 are more sensitive for spindle cell melanoma) (70); and CD31, CD34 and ERG1 (for angiosarcoma and epithelioid hemangioendothelioma).