The Kips Bay Medical eSVS Mesh is designed to address the limitations of saphenous vein grafts
used in coronary artery bypass graft (CABG) surgery.
Angiogram showing total occlusion of LAD and patent saphenous vein grafts
Up to 25% of saphenous vein grafts
occlude in the first postoperative year, and annual occlusion rates thereafter are l%-2% until year 5 and 4%-5% from years 5-10.
A coronary angiogram demonstrated that the LIMA and saphenous vein grafts
were patent and not narrowed.
Brilakis said that some of the previous studies have indicated that patients receiving drug-eluting stents in saphenous vein grafts
may not reduce the risk of re-narrowing and may be associated with increased risk of death.
Although arterial grafts have better long-term outcomes, venous grafts, specifically saphenous vein grafts
(SVGs), are more readily available.
In an analysis that adjusted for several baseline differences, patients who were diagnosed with depression at entry had a 40% increased risk of having substantial atherosclerosis progression in their saphenous vein grafts
, compared with patients who were not depressed at baseline, said Dr.
The TriActiv System, in its current indication, is designed to prevent heart attacks during the treatment of saphenous vein grafts
(SVGs) in patients who previously received coronary bypass surgery, but now have blockages in the grafts.
The eSVS Mesh device is designed to prevent saphenous vein grafts
a company engaged in research, development, manufacturing and marketing of heterologous tissue covered stents, announced that the US Food and Drug Administration (FDA) has granted HUD (Humanitarian Use Device) designation to Over and Under(R) and Aneugraft(R) Pericardium Covered Stents for treatment of perforations and dissections of native coronary arteries and Saphenous Vein Grafts
The relationship regarding postoperative inadequacies or occlusions of saphenous vein grafts
with the degree of stenosis in the native coronary arteries is not clear.
After adjustment for baseline differences, patients depressed at entry had a 40% increased risk of having substantial atherosclerosis progression in their saphenous vein grafts
, compared with patients who were not, which was significant, said Dr.