We were the first to prove hERG as the target for adverse cardiac events linked to Seldane
(terfenadine), Propulsid (cisapride), and Nizoral (ketoconazole), and the pioneer in functional, cell-based ion channel testing to predict cardiac side effects produced by non-cardiac drugs," said ChanTest Chief Executive Officer, Dr.
If you take Seldane
, and you don't think it's working the way it should, it may be because you're drinking a fruit juice that blocks some of its absorption.
Besides Vioxx, other drugs that were taken off the market after their initial approval include allergy-relieving Seldane
, antidiabetes Rezulin, and the cholesterol-lowering Baycol.
Consider three prescription drugs once in common use: Seldane
, Hismanal, and Propulsid.
Recently it was accidentally discovered that grapefruit juice can enhance the absorption of a number of drugs, including the sedative Halcion (triazolam), the antihistamine Seldane
(now off the market), and the immuno-suppressant cyclosporine, among others (Rodvold and Meyer 1996).
Another drug which stayed on the market for a number of years after it should have been banned is Seldane
, a widely prescribed antihistamine.
60) Manufacturers have used advertisements in both electronic and print media to promote the use of products such as the antihistamine Seldane
, the anti-baldness drug Rogaine, and the angina drug Procardia, among many others.
In February, the antihistamine, Seldane
, was withdrawn by Hoechst Marion Roussell.
Earlier this year, the Food and Drug Administration issued a warning about Seldane
, the widely used antihistamine for allergies.
Terfenadine is sold under brand names including Triludan, Triludan Forte, Seldane
, Terfenor, Aller-Eze Clear, and Boots Antihistamine Tablets.
Food and Drug Administration proposed a ban on the widely prescribed allergy drug Seldane
because it can cause a rare, but fatal, heart rhythm when taken with other drugs.
Allergy sufferers rejoiced when Seldane
appeared on the market -- the first antihistamine to relieve the sneezing, watery eyes, and runny noses of pollen allergy without making the user sleepy.