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Sickled

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
sick·le  (skl)
n.
1. An implement having a semicircular blade attached to a short handle, used for cutting grain or tall grass.
2. The cutting mechanism of a reaper or mower.
v. sick·led, sick·ling, sick·les
v.tr.
1. To cut with a sickle.
2. To deform (a red blood cell) into an abnormal crescent shape.
v.intr.
To assume an abnormal crescent shape. Used of red blood cells.
adj.
Shaped like the blade of a sickle; crescent-shaped: a sickle moon.

[Middle English sikel, from Old English sicol, from Vulgar Latin sicila, from Latin scula; see sek- in Indo-European roots.]


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The vaso-occlusion of small vessels in ribs, sterum, or other bones by sickled hemoglobin may also by itself be responsible for acute pain crisis.
Grand battements end surprisingly: a bent knee across the chest, the foot awkwardly sickled.
Hemoglobin-S does not transfer nitric oxide from heme to thiol as well as normal hemoglobin during S-nitrosohemoglobin conformation The symptoms of sickle-cell disease are attributed to the physical obstruction of blood vessels by distorted or sickled and rigid RBCs.
 
 
 
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