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gene therapy
(redirected from Somatic gene therapy)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
gene therapy
n.
The treatment of certain disorders, especially those caused by genetic anomalies or deficiencies, by introducing specific engineered genes into a patient's cells.

gene therapy
n
(Life Sciences & Allied Applications / Genetics) the replacement or alteration of defective genes in order to prevent the occurrence of such inherited diseases as haemophilia. Effected by genetic engineering techniques, it is still at the experimental stage

gene therapy
The treatment of a disorder or disease, especially one caused by the inheritance of a defective gene, by replacing defective genes with healthy ones through genetic engineering.
Translations
gene therapy
n (Med) → Gentherapie f


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The invention also provides improved methods for somatic gene therapy capitalizing on enhanced gene transfer, hematopoietic cellular populations, and novel constructs for enhancing retroviral-mediated DNA transfer into cells and their use.
In 1985, the US National Institutes of Health (NIH) approved somatic gene therapy trials, but said that it would not accept proposals for germline manipulation "at present.
[5,7-13] Genetic treatment strategies (pharmacogenetics) may include use of antisense oligonucleotides designed to bind to a region of a gene or messenger RNA to block transcription or translation or somatic gene therapy to transfer and express an exogenous normal gene into a patient's somatic cells.
 
 
 
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