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Southern blot analysis

   Also found in: Medical 0.01 sec.
Southern blot analysis
n.
A technique for identifying specific sequences of DNA in which DNA fragments are separated by electrophoresis, transferred to nitrocellulose, and identified with a suitable probe.

[After Edwin Mallor Southern (born 1938), British biochemist.]


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Previously, researchers developed tests to detect H5N1 virus by using conventional RT-PCR (6-8) and confirmed the results by Southern blot analysis (6) or restriction fragment length polymorphism-based strategy (8).
3,10-12) Furthermore, the Southern blot analysis of EBV-associated Hodgkin lymphoma has demonstrated that the EBV is monoclonal in these cases, indicating that the virus was likely present before neoplastic transformation.
 
 
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