Subthalamic


Also found in: Medical.
Related to Subthalamic: Subthalamic nucleus of Luys

Sub`tha`lam´ic


a.1.(Anat.) Situated under the optic thalamus.
References in periodicals archive ?
It consists of several structures, including the striatum (entailing the caudate and putamen), the globus pallidus (divided into internal and external segments), the substantia nigra, and the subthalamic nucleus (Herrero et al.
Electrical stimulation of a deep-seated brain region, the subthalamic nucleus (STN), has been shown to significantly improve patients motor function and quality of life.
DeLong's research -- spanning a 40-year career in medicine and science -- identified the anatomical brain circuits involved in the clinical features of Parkinson's disease and a novel target for surgical intervention, the subthalamic nucleus, a portion of the basal ganglia, brain structures located deep in the brain.
Alternative surgical procedures such as bilateral globus pallidus interna stimulation and bilateral subthalamic nucleus stimulation can be used in Parkinson's disease patients under certain circumstances.
Additionally, the Myoton-3 has successfully discriminated between on-off responses to medication and subthalamic stimulation in individuals with Parkinson disease for relaxed arm and hand muscles [61-62] and compared with healthy, matched controls [12,63].
In a clinical study published in the New England Journal of Medicine, a six-month study of patients younger than 75 with severe motor complications of PD demonstrated that neurostimulation of the subthalamic nucleus was more effective than medical management alone.
This condition is a result of absent subthalamic nucleus inhibition, which increases motor activity through the motor thalamus.
Normally the GPe inhibits firing of the subthalamic nucleus (STN), so when the GPe is inhibited, this allows the STN to fire more freely.
The addition of subthalamic stimulation to medication therapy not only improved the quality of life of patients with early Parkinson's disease and mild levodopa-induced motor complications but also reduced their subsequent motor disability in a randomized trial conducted in French and German centers.
18) The subthalamic nucleus is quite atrophic virtually only in progressive supranuclear palsy (FTLD-tau [PSP]) (Figure 5), and the cerebellar dentate nucleus is also generally "indistinct" (19) (Figure 6).
Dorsal striatum: A pair of nuclear masses that form the basal ganglia, along with the subthalamic nucleus and the substantia nigra.
Researchers evaluated 89 patients who were stimulated in a part of the brain called the globus pallidus interna and 70 patients who were stimulated in a different part of the brain called the subthalamic nucleus.