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succinate
(redirected from Succinate dehydrogenase)

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
suc·ci·nate  (sks-nt)
n.
A salt or an ester of succinic acid.

succinate [ˈsʌksɪˌneɪt]
n
(Chemistry / Elements & Compounds) any salt or ester of succinic acid
[from succin(ic) + -ate2]

succinate  (sks-nt)
A salt or ester of succinic acid.


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The capacity of classic markers for mitochondrial density, ie, the capacity of citrate synthase (CS) and succinate dehydrogenase (SDH), as well the capacity of cytochrome c oxidase (COX) and beta-hydroxyacyl-CoA dehydrogenase (HAD), was determined in homogenized muscle biopsy samples obtained from the vastus lateralis muscle of nonexercising healthy young (age 20 [+ or -] 2 yr) subjects (31 women, 7 men).
Our working hypothesis is that tryptamine inhibits succinate dehydrogenase (SDH), a Krebs cycle enzyme that converts succinate to fumerate ultimately increasing ATP levels.
A Qualitative and Quantitative Assessment in Muscle Succinate dehydrogenase (SDH) has frequently been used as a qualitative histochemical marker for the presence of "ragged-red fibers" in skeletal muscle, which indicates abnormally increased numbers of mitochondria; this defect also is detected by the modified Gomori trichrome stain.
 
 
 
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