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sympatholytic
(redirected from Sympatholytics)

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
sym·pa·tho·lyt·ic  (smp-th-ltk)
adj.
Opposing the physiological effects caused by stimulation of the sympathetic nervous system: a sympatholytic treatment.


sympatholytic [ˌsɪmpəθəʊˈlɪtɪk] Med
adj
(Medicine)
a.  inhibiting or antagonistic to nerve impulses of the sympathetic nervous system
b.  of or relating to such inhibition
n
(Medicine / Pharmacology) a sympatholytic drug Compare sympathomimetic
[from sympath(etic) + -lytic]


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The sympatholytics are also recommended because they block the peripheral autonomic hyperarousal in PTSD, but they can also cause troublesome side effects, including hypotension.
64) Central [alpha]-2 agonists (clonidine) may cause peripheral vasoconstriction via crossover stimulation of peripheral postsynaptic [alpha]-1 receptors, (65) while sympatholytics such as methyldopa (66) may cause transient hypertensive exacerbation before their hypotensive effects become manifest.
Hypotension with a relative bradycardia could be due to sympatholytics (think of beta-blockers, opiates), membrane depressants (think of quinidine, tricyclics) and others (think of fluoride, organophosphates, sedative-hypnotics).
 
 
 
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