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ligase
(redirected from Sythetase)

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
li·gase  (lgs, -gz)
n.
Any of a class of enzymes that catalyze the linkage of two molecules, generally utilizing ATP as the energy donor. Also called synthetase.

[Latin ligre, to bind; see leig- in Indo-European roots + -ase.]

ligase [ˈlaɪˌgeɪz]
n
(Life Sciences & Allied Applications / Biochemistry) any of a class of enzymes that catalyse the formation of covalent bonds and are important in the synthesis and repair of biological molecules, such as DNA


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The oxidative activation of etoposide can be brought about by the array of enzymes, which also include cytochrome p450 monooxygenases, prostaglandin sythetase and tyrosinase, which ultimately manifest into cytotoxicity (Kagan, et al.
 
 
 
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