TRALI


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TRALI

abbreviation for
1. (Pathology) transfusion-related acute lung injury: a potentially fatal condition that can affect a female blood donor who has been pregnant
2. (Medicine) transfusion-related acute lung injury: a potentially fatal condition that can affect a female blood donor who has been pregnant
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References in periodicals archive ?
In 2004, the European Haemovigilance Network (EHN) proposed criteria for the diagnosis of TRALI, which is summarized in Table 1.
Una forma de mitigacion ha sido comprobada por la Cruz roja Americana y otros paises con sistema de hemovigilancia, con reduccion de mortalidad por TRALI desde 2006, adoptando la donacion por hombres para casos con riesgo, disminuyendo asi hasta 50% la mortalidad, no en grupo sanguineo AB que permanece sin cambios, igual con transfusiones masivas.
TRALI occurs where transfused plasma contains human leucocyte antigen (HLA) antibodies.
In fact, 60% of TRALI fatalities were a result of plasma transfusions.
An inquest heard Mair Griffiths, 64, a child minder from Springfield Drive, Buckley, probably died from an unusual blood transfusion complication, TRALI, which causes acute lung injury.
TRALI is defined as an acute syndrome with severe shortness of breath within 4-6 hours of a transfusion, with no signs of fluid overload, bilateral pulmonary infiltrates on chest x-ray, and changes in arterial oxygenation, in the absence of other detectable causes.
The Japanese Red Cross Society conducted the first study in Japan on the complication known as transfusion-related acute lung injury, or TRALI, based on international diagnosis standards.
Chapters on TRALI and transfusion-associated circulatory overload (TACO) reflect recent improved understanding of these complications since the third edition.
Acute Delayed Haemolytic 2 0 Allergic 25 0 Febrile 100 0 TRALI 0 0 TACO 0 0 Ta-GVHD 0 0 Infections 0 0 Iron overload 0 38 Total 127 38 Note: Table made from bar graph.
Un estudio de cohortes realizado en 2007 en los Paises Bajos demostro que el uso de plasma fresco congelado proveniente exclusivamente de hombres redujo en 33% la frecuencia de TRALI (10), y en 2010 la Cruz Roja americana publico un estudio que demostro disminucion de 21% en la frecuencia de TRALI luego de aumentar la proporcion de transfusiones de plasma proveniente de hombres, de 55% en el ano 2006 a 95% en 2008(11).