New developments in managing transient ischemic attack
and acute stroke.
A transient ischemic attack
is characterized as a brief episode of blood loss to the brain, creating symptoms such as numbness or tingling, temporary loss of vision, difficulty speaking, or weakness on one side of the body.
The Management of Atherothrombosis with Clopidogrel in High-Risk Patients with Recent Transient Ischemic Attacks
or Ischemic Stroke (MATCH) trial was conducted with 7,599 patients in 28 countries and is the largest study to date with such a high-risk population.
This study tested whether treatment with 80 mg of atorvastatin (Lipitor) daily cut the risk of stroke in patients without known coronary disease who had a stroke or transient ischemic attack
during the previous 6 months.
According to the Supplement to the Guidelines for the Management of Transient Ischemic Attacks
published in the November 1999 issue of Stroke, the Journal of the American Heart Association, the combination of extended-release dipyridamole and aspirin found in AGGRENOX may also be a more favorable treatment option for the prevention of secondary stroke than other antiplatelet agents.
The study is a prospective, randomized, multi-center, multi-national trial designed to demonstrate safety and effectiveness of the GORE HELEX Septal Occluder for PFO closure in patients with a PFO and history of cryptogenic stroke or imaging confirmed Transient Ischemic Attack
For the first time, the guidelines address stroke as a broad continuum of related events, including ischemic stroke, non-ischemic stroke and transient ischemic attack
Clinical ischemic events were defined as re-onset of angina pectoris (chest pain) needing medical treatment, myocardial infarction (heart attack), ischemic stroke, or transient ischemic attack
Scientists found a linear relationship between the risk of stroke, transient ischemic attack
(TIA), MI, or all of these adverse outcomes and the total number of abuse types they experienced as children (physical, emotional or sexual abuse, or physical or emotional neglect.
The UK Transient Ischaemic Attack Aspirin Trial randomized 2,449 patients over age 40 who had already had a transient ischemic attack
or mild ischemic stroke to receive daily doses of either 1,200 mg or 300 mg of aspirin, or placebo.
These new guidelines recommend low-dose aspirin (50 mg to 325 mg) as safe and effective therapy to prevent a stroke in those patients who have already had a stroke, or transient ischemic attack
Scientists developed a new tool known as the "Recurrence Risk Estimator at 90 days" or "RRE-90 score" to calculate a person's risk of having another stroke within three months by looking at risk factors of stroke, such as history of mini-stroke, or transient ischemic attack
(TIA), age and the type of first stroke the person experienced, along with information from brain scans.