tricyclic antidepressant

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Related to Tricyclic antidepressants: SSRI

tricyclic antidepressant

n. Abbr. TCA
Any of a group of antidepressant drugs, such as amitryptyline, that contain three fused benzene rings and that block the reuptake of the neurotransmitters norepinephrine and serotonin in the central nervous system.
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Noun1.tricyclic antidepressant - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
amitriptyline, amitriptyline hydrochloride, Elavil - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications
antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects
clomipramine - a tricyclic antidepressant drug
desipramine - a tricyclic antidepressant drug that activates the psychomotor system
Adapin, doxepin, doxepin hydrochloride, Sinequan - a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)
Imavate, imipramine, impramine hydrochloride, Tofranil - a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression
nortriptyline, Pamelor - a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs
protriptyline - tricyclic antidepressant used to treat clinical depression
Surmontil, trimipramine - tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia
References in periodicals archive ?
Tricyclic antidepressants and monoamine oxidase inhibitors are typically not prescribed as initial treatment because of safety concerns and adverse effects.
The global anxiety disorders and depression treatment market segmentation is based on drug class (selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake, atypical antipsychotics, tricyclic antidepressants, tetracyclic antidepressants, monoamine oxidase inhibitors, benzodiazepines, beta-blockers, anticonvulsants).
The results suggest that fluoxetine causes less bone resorption than other selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors, or tricyclic antidepressants and "may be a safer choice for a cohort already predis-posed to poorer brain health," the researchers concluded in a poster presented at the 18th Congress of the International Psychogeriatric Association.
The results suggest that fluoxetine causes less bone resorption than other selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors, or tricyclic antidepressants and "may be a safer choice for a cohort already predisposed to poorer brain health," the researchers concluded in a poster presented at the 18th Congress of the International Psychogeriatric Association.
2) Central nervous system toxicity of tricyclic antidepressants may manifest as confusion, agitation, hallucinations, coma, myoclonus, or seizures.
Biofeedback and tricyclic antidepressants appear to be effective as prophylactic treatment for chronic tension headaches, although tricyclic antidepressants have more adverse effects (strength of recommendation [SOR]: B, meta-analysis of randomized controlled trials [RCTs] and prepost trials).
26, 2015 in JAMA Internal Medicine, people who took high doses of tricyclic antidepressants such as doxepin (Sinequan), diphenhydramine (Benadryl), older antihistamines such as chlorpheniramine (Chlor-Trimeton), or antimuscarinic drugs for bladder control, such as oxybutynin (Ditropan) for longer than three years were significantly more likely to develop dementia.
4) Tricyclic antidepressants also are recommended for treating burning, stabbing, or tingling sensations.
Tricyclic antidepressants (TCAs) are widely prescribed for several indications in South Africa.
Of these, 55 percent were for selective serotonin reuptake inhibitors (SSRIs), 32 percent for tricyclic antidepressants (TCAs), and 13.
Compared directly with tricyclic antidepressants, SSRIs were associated with significantly higher rates of all-cause death (adjusted hazard ratio, 1.
Selective serotonin reuptake inhibitors (SSRIs) are more likely to cause death and issues such as heart attack, stroke, falls and seizures than older tricyclic antidepressants (TCAs), according to a study published in the British Medical Journal (BMJ).