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Umbelliferone

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Um`bel`lif´er`one
n.1.(Chem.) A tasteless white crystalline substance, C9H6O3, found in the bark of a certain plant (Daphne Mezereum), and also obtained by the distillation of certain gums from the Umbelliferæ, as galbanum, asafetida, etc. It is analogous to coumarin. Called also hydroxy-coumarin. Its strong fluorescence under ultraviolet light makes it useful in analytical biochemistry, as, for exmple, to detect phosphatase activity by hydrolysis of umbelliferyl phosphate.


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simple coumarins : umbelliferone, scopoletin - terpenoids mainly : .
The herb contains flavonoids, carotenoids, hydroxycoumarins umbelliferone and skimmine, also tannins, caffeic acid, fatty acids, lectins, etc (Antonyuk 2004, Chevallier 2000, PDR, 1998, Yakovlev and Blinova 1999).
The alternative metabolic route of 3-hydroxylation is also discussed as a possible pathway in humans with defects in the main route of coumarin-metabolism, creating umbelliferone and its subsequent glucuronidation to 7-hydroxycoumaringlucuronide (Cox et al.
 
 
 
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