vinca alkaloid


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vinca alkaloid

n
(Pharmacology) med any of a group of alkaloids obtained from the periwinkle Vinca rosea, such as vinblastine and vincristine, that interfere with cell division and are used in the treatment of cancer
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3) Additionally, the use of a vinca alkaloid in conjunction with a steroid is associated with better outcomes than either of these agents alone.
Vintafolide is an investigational, injectable SMDC featuring folate (vitamin B9) linked to a potent vinca alkaloid cytotoxic agent, desacetylvinblastine hydrazide (DAVLBH).
The chemotherapy drug is a very potent vinca alkaloid.
In 1976, Potier's team discovered that the Tubulin test proved a semi-synthesis of one vinca alkaloid compound to be active, showing promise as an anticancer drug.
Conophylline (27): Conophylline (27) is a vinca alkaloid from T.
Patients who fail to improve on this regimen should be given a course of either a vinca alkaloid or etoposide.
Vintafolide is an investigational, proprietary, injectable SMDC consisting of folate (vitamin B9) linked to a potent vinca alkaloid cytotoxic agent, desacetylvinblastine hydrazide (DAVLBH).
Vintafolide is a proprietary, injectable, conjugate consisting of folate (vitamin B9) linked to a potent vinca alkaloid anti-cancer agent, desacetylvinblastine hydrazide (DAVLBH).
Vintafolide is an investigational proprietary, injectable, SMDC consisting of folate (vitamin B9) linked to a potent vinca alkaloid chemotherapy agent, desacetylvinblastine hydrazide (DAVLBH).
GTx-230: An orally available tubulin antagonist discovered by GTx researchers, GTx-230 has the potential to treat cancer and cancer refractory to taxane and vinca alkaloid therapy.
Vintafolide is a conjugate of the vitamin folate and a super-potent vinca alkaloid.