Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden
Thus, a treatment duration of 4 weeks with 3 or 4 potent DAAs is not sufficient to cure HCV infection in most patients," she wrote, noting, however, that "some patients are capable of achieving SVR with 4 weeks of therapy, which could be attributable to the presence of several favorable factors, such as early fibrosis, low viral burden
, and absence of resistance-associated variants.
Reduced viral burden
in paralytic compared to furious canine rabies is associated with prominent inflammation at the brainstem level.
Nucleic acid testing for viral burden
and viral genotyping.
The preclinical studies performed at the Walter and Eliza Hall Institute of Medical Research have indicated that SMAC-Mimetics decreases the viral burden
in mice with human Hepatitis B Virus by inducing apoptosis of virally infected hepatocytes while sparing the non-infected cells.
Children with fevers tended to carry a heavier viral burden
, both in the number and type of viruses.
Although the degree of immunodeficiency and viral burden
are monitored routinely, immune activation status is not currently tested in HIV infection.
Results from Phase I and Phase IIA human clinical trials have shown that PRO 140 can significantly reduce viral burden
in people infected with HIV.
Copy-years viremia as a measure of cumulative human immunodeficiency virus viral burden
One of two drugs, zidovudine (ZDV, also known as AZT), has demonstrated some benefit in controlled trials in naturally infected cats (ZDV has been shown to lower viral burden
in both acute and chronic infection, and to improve clinical signs in chronically infected cats).
in genital secretions determines male-to-female sexual transmission of HIV-1: a probabilistic empiric model.
Sensitivity, specificity, and positive predictive value of oral opportunistic infections in adults with HIV/AIDS as markers of immune suppression and viral burden