Also found in: Medical, Wikipedia.


The use of genetically engineered viruses to infect and kill tumor cells.
References in periodicals archive ?
In contrast to single-agent pembrolizumab therapy, responders to the combination regimen included patients with very low levels of CD8+ T-cell infiltrates or negative interferon-gamma (IFN-gamma) gene signatures in baseline tumor biopsies, suggesting that oncolytic virotherapy might make anti-programmed death-1 (PD-1) therapy more effective by altering the tumor microenvironment, the researchers concluded.
We look forward to working with Randox and to generating novel product candidates which combine the merits of oncolytic virotherapy and local delivery of therapeutic payloads.
Evidence suggests that the host immune response seems to reduce the effectiveness of oncolytic virotherapy.
com)-- Aina Muceniece Virotherapy Foundation hereby announces an international artwork competition, within the framework of which any professional, emerging artist or enthusiast without any age, professional or educational requirements is invited to submit their newly created artwork dedicated to the struggle with oncological disease or victory over it.
2 It wasn't until late twentieth century that fundamental understanding of virus was established, thus it was from this point forward that research efforts in establishing Virotherapy gained momentum,2 which uses a genetically modified virus to treat cancers.
This review will explore the current state of oncolytic virotherapy in treating glioma.
The integrated firm's range includes eight oncolytic virotherapies in clinical development, seven in late-stage preclinical development and validated oncolytic virotherapy platforms.
These may include novel platform technologies to address so far undrugable targets, new generation vaccines and/or new biological entities, such as oncolytic virotherapy.
Virotherapy is an experimental treatment for cancer based on viruses, which scientists say could revolutionise cancer therapy during the next decade.
Speaking to the Times, Professor Kevin Harrington said that tests of virotherapy had proven a success so far.
After years of study the first laboratory for virotherapy as a treatment for cancer was established at the institute, which led to the development of the medicine Rigvir.