Waterhouse-Friderichsen syndrome

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Related to Waterhouse-Friderichsen syndrome: meningitis
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Noun1.Waterhouse-Friderichsen syndrome - syndrome associated with bacterial meningitis; marked by sudden high fever and skin discoloration and petechiae with hemorrhage into the adrenal glands and cardiovascular collapse
syndrome - a pattern of symptoms indicative of some disease

Wa·ter·house-Frid·er·ich·sen syn·drome

n. Waterhouse-Friderichsen, síndrome de, hemorragia aguda en las glándulas suprarrenales con hemorragia en la piel asociada a un repentino choque bacteriogénico agudo.
References in periodicals archive ?
A common problem in these patients is hypothalamic-pituitary-adrenal axis failure, including structural damage to the adrenal glands from haemorrhage, such as in Waterhouse-Friderichsen syndrome (1).
5) The onset of Waterhouse-Friderichsen syndrome is usually abrupt, and patients present with lever, chills, nausea, vomiting, myalgia, arthralgia, and a generalized rash.
Previous reports from University of Chicago have described a cluster of 4 cases in which USA400 isolates caused empyema and sepsis syndrome with some features of toxic-shock syndrome (4); 3 children died with necrotizing pneumonia and Waterhouse-Friderichsen syndrome due to a PVL-positive, MLST-identified type 1 strain (15).