Wiskott-Aldrich syndrome

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Related to Wiskott-Aldrich syndrome: Ataxia-telangiectasia, DiGeorge syndrome

Wis·kott-Al·drich syndrome

 (wĭs′kŏt-ôl′drĭch, -ŏl′-, vĭs′-)
A hereditary sex-linked recessive disorder characterized by chronic eczema, recurring infections, and a decrease in the number of white blood cells and platelets.

[After Alfred Wiskott (1898-1978), German pediatrician, and Robert Anderson Aldrich (1917-1998), American physician.]
References in periodicals archive ?
Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndrome.
However, his family were later warned that Wiskott-Aldrich syndrome was incurable and few children lived beyond two years of age.
With Wiskott-Aldrich syndrome, the sufferer has a faulty immune system making them more susceptible to disease.
Thrombocytopenia and the presence of microthrombocytes in male infants suggest Wiskott-Aldrich syndrome.
Prior to the AIDS epidemic, PML was rarely seen in other immunocompromised patients occurring usually as a terminal event such as in cases of leukemia, lymphoma, systemic lupus erythematosus (SLE), Wiskott-Aldrich syndrome, and severe combined immunodeficiency (SCID).
The remaining 2 samples were from infants diagnosed with Omenn syndrome and Wiskott-Aldrich syndrome.
Petechial rashes associated with eczema or seborrheic dermatitis-like lesions can also be seen in children with Langerhans cell histiocytosis or Wiskott-Aldrich syndrome.
For LYG, increased frequency is associated with both congenital and acquired immunodeficiency, such as X-linked lymphoproliferative syndrome, Wiskott-Aldrich syndrome, and HIV/ AIDS in which T-cell surveillance is deficient (8).
The first of these will be metachromatic leukodystrophy (MLD) and Wiskott-Aldrich Syndrome (WAS).
Jack suffers from Wiskott-Aldrich syndrome, a rare immune deficiency affecting one in four million people.
London, June 22 (ANI): Researchers at Baylor College of Medicine say that they have made a new finding regarding the Notch signalling pathway in sensory organ precursor cells in the fruit fly that may help unravel the mystery behind an immunological disorder called WisKott-Aldrich syndrome.