8-chlo·ro·the·oph·yl·line

(āt′klô′rə-thē-ŏf′ə-lĭn)

A stimulant, C₇H₇N₄O₂Cl, that is used to form a salt with certain pharmaceutical drugs, such as diphenhydramine.

[8-, conventional numbering of the position in the compound's purine ring to which the chlorine atom is attached + chloro- + theophylline.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Mentioned in

dimenhydrinate

References in periodicals archive

Castro, "Optimization and validation of a method for the determination of caffeine, 8-chlorotheophylline and diphenhydramine by isocratic high-performance liquid chromatography.

Application of HPTLC with Densitometry for Evaluation of the Impact of External Factors on Contents of Diphenhydramine in Its Solutions

For the measurement of caffeine concentrations by HPLC, 8-chlorotheophylline (internal standard) was added to the samples, and proteins in the samples were precipitated with acetonitrile.

Falsely increased urinary caffeine attributable to contamination by urine test strips

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