The intermediate 2 was characterized by FT-IR (cm-1) 3244 (1AdegNH str.), 3115 (2AdegNH str.) and 1698 (C=O amide).Finally, the synthesis of titled compounds, (3a-3f) was afforded by reacting compound 2 with different aromatic and heteroaryl aldehydes in presence of acidic condition via nucleophilic
addition reaction.
It can generate pentabasic 1,3-oxazole which is an important compound in both synthetic chemistry [5] and biochemistry [6-9] through [3 + 2] ring
addition reaction with alkyne.
We have recently proposed an efficient synthetic process for dehydrative glycosylation that consists of two elemental reactions, intramolecular dehydration and the subsequent
addition reaction (Fig.
Elastosil LR 3020/60 is a two-component liquid silicone rubber compound which is optimized for injection molding and vulcanizes rapidly via a platinum-catalyzed
addition reaction. A special feature is said to be its high steam resistance once the silicone is cured.
PDMS with either vinyl or hexenyl groups is crosslinked with hydride-functional PDMS chains via a hydrosilylation or
addition reaction. Curing is very rapid, and, in fact, inhibitors, such as acetylenic alcohols and maleates, are often added to the coating formulation to prevent unwanted cure at room temperature and to maximize working bath life.
In general, a combination of an epoxy resin and a primary amine leads to two principal reactions of (a) the
addition reaction of a primary amine hydrogen to an epoxy group to form a secondary amine and (b) the
addition reaction of an amine hydrogen in the secondary amine to another epoxy group to create a tertiary amine [21, 22],
In the field of advanced organic synthesis, Michael
addition reaction is one of the most powerful tools for carbon-carbon bond construction reactions [1-6].
After the complete
addition reaction mixture was allowed at room temperature and refluxed for 2 to 3h in water bath, the reaction mixture was allowed to cool at room temperature and the precipitate obtained was filtered, dried, and recrystallized from ethanol to give a pure 4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide 3 as a white crystal in 85% yield, Mp--128-130[degrees]C.
The CASSCF calculations present that the evolution path from FC to CI is barrierless for asynchronous mode while it has to overcome 0.8 eV barrier in synchronous
addition reaction. It suggests asynchronous pathway is a favored predominant pathway for [2 + 2] photocycloaddition reaction between benzene and ethylene, in accord with simulation results.
addition reaction - a chemical reaction in which one molecule is added to another