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Care monitoring company Edwards Lifesciences Corporation (NYSE:EW) disclosed on Friday that it has receipt approval from the US Food and Drug Administration (FDA) to expand use of the SAPIEN 3 and SAPIEN 3 Ultra transcatheter heart valve systems to the treatment of severe, symptomatic aortic stenosis (AS) patients at low risk of open-heart surgery.

Edwards wins FDA approval for SAPIEN 3 TAVR for low-risk patients with severe, symptomatic aortic stenosis

The researchers randomly assigned 725 patients (mean age 74) with severe symptomatic aortic stenosis to the TAVR treatment group and another 678 patients to an open-heart surgery group.

A Game-Changer for Aortic Stenosis: Two ground-breaking studies suggest that transcatheter aortic valve replacement is a safe and effective alternative to open-heart surgery

"Our new research has shown that platelet-derived TGF-beta1 contributes to scar tissue formation in the aortic valve, leading to aortic stenosis," said Ahamed, who joined OMRF from New York's Rockefeller University in 2015.

OMRF reports heart failure research

Aortic stenosis is a narrowing of the aortic valve that occurs because of calcium deposits that cause the valve to narrow.

RWJ Barnabas Health plays vital role in landmark cardiac study

In patients with aortic stenosis (AS) the concentration of NT-proBNP was significantly high (5990.2+-5893 pg/ml) (p< 0.001 vs.

Analysis of NT-proBNP and uric acid due to left ventricle hypertrophy in the patients of aortic valve disease

Long-term exposure to higher blood pressure is a strong and potentially modifiable risk factor for aortic stenosis and regurgitation at every level of typical blood pressure, not only in those who are classified as having hypertension.

Elevated BP is linked to aortic valve disease

If you have aortic stenosis, the left ventricle has to work harder to pump blood into the aorta, which is the main outlet for blood to continue on into the body.

Help for Ailing Heart Valves: Heart valves that don't function correctly raise your risk for a range of complications

Among the clinical scenarios of the cases are critical aortic stenosis, stress-induced cardiomyopathy (Takotsubo cardiomyopathy), multi-vessel disease: demand ischemia causing ST elevations, hyperkalemia, and critical aortic stenosis.

STEMI vs. FEMI: A Real STEMI or a Fake STEMI (online access included)

In this paper, we report a case of infective endocarditis following aortic stenosis with mild regurgitation in a pregnant woman having a congenital bicuspid aortic valve and discuss its outcomes.

Unusual presentation of infective endocarditis during pregnancy: A case report

Critical aortic stenosis (CAS) is a rare and important disease in newborns.

Aortic Wall Injury: Intimal Flap Formation after Aortic Balloon Valvuloplasty, a Rare Complication