A total of 24 compounds were identified during the study, major compounds are Aromadendrene oxide-(1) (53.57%) and Asarone (17.55%).
The major compounds identified in the study are Aromadendrene oxide-(1) and Asarone The plant extracts showed strong activity against selected Gram positive bacteria and yeast, while no activity against Gram negative bacteria mold`.
Asarone is found in the Asarum family of spices that includes Acorus calamus.
Monoterpene hydrocarbons, sequestrine ketones, (trans- or Alpha)
Asarone (2,4,5-trimethoxy-l-propenylbenzene), and beta-asarone (cis-isomer) and eugenol were also identified (Balakumbahan et al.
Bioanalytical investigation of
asarone in connection with acorus calamus oil intoxications.
Asarone, a component of the plant, has been reported to have tranquilizing action Menon and Dandiya, (1967), which validates the traditional medicinal use of the plant as a sedative.
This may be due to the ovicidal action of the active component "
asarone" of sweet flag as shown by Schmidt and Risha (1990) and Zaidi et al.
Keywords:
Asarone Colorectal cancer Lamins Cell senescence Oct-1
Monograph on Beta
Asarone. WHO Food Additive Series No.
Among aromatics with allyl, propenyl and/or methoxy side chains, safrole and
asarone showed similar trypanocidal activity, safrole being a little bit more active than
asarone.
Diaz F, Contreras I, Flores R, Tamariz J, Labarrios F, Chamorro G, Munoz H (1990) An efficient synthesis of alpha
asarone. Org Prep Proc Int 23: 133-138