Benzalkonium chloride + fluazinam and procymidone were the most effective treatments.
Later that year Alcon changed the formulation of their prostaglandin analogue, travoprost (Travatan) and in early 2011 that of travoprost with timolol (Duotrav) replacing the preservative
benzalkonium chloride with Polyquad.
Raiskup, "Pharmacological modification of the epithelial permeability by
benzalkonium chloride in UVA/Riboflavin corneal collagen cross-linking," Current Eye Research, vol.
* Propylene glycol: Like
benzalkonium chloride, it can cause not only allergic contact dermatitis, but irritant contact dermatitis marked by nonimmunologically related burning and stinging.
Use of
benzalkonium chloride (BC) as an antiseptic should be discontinued, concluded Dr.
The zinc nasal gel consisted of zinc gluconate in an emulsion of
benzalkonium chloride, glycerin, hydroxyethylcellulose, sodium chloride, and sodium hydroxide; its pH level was 7.2.
Imprimis will not dispense these formulations with preservatives such as
benzalkonium chloride, which is typically used in many topical glaucoma drugs.
According to Brian Sansoni, VP-communications and membership and VP-sustainability initiatives, more than a year ago FDA granted a deferral of rulemaking for one year for the three active ingredients that ACI is supporting (
benzalkonium chloride (BAC), benzethonium chloride (BZT) and chloroxylenol (PCMX)).
BAC-D provides a nonflammable, nonalcohol-based alternative containing
benzalkonium chloride, a Food and Drug Administration monograph drug, and it doesn't irritate tissue and is proven by major university testing to offer residual protection against germs and bacteria for three or more hours after application, the company says.