Histopathological examination: increased intraepithelial lymphocytes,
cryptal hyperplasia and loss of villi (a: HE, x50; b: HE, x100).
In the non-neoplastic intestinal mucosa, villous atrophy,
cryptal hyperplasia, intraepithelial lymphocytosis, and lymphoplasmacytic infiltration in lamina propria were observed (Figure 2).
Beyond the standard white light endoscopy (WLE), studies using dye-based CE with magnification endoscopes (cresyl violet plus zooming) proved a lower clinical and histologic inflammation in UC patients having
cryptal openings and a network pattern [11].
(37.) Stanton MT et al., "Diagnostic Ultrasound Induces Change within Numbers of
Cryptal Mitotic and Apoptotic Cells in Small Intestine," Life Sciences 68, no.
Representative colon tissue sections from mice in the control group showed intact surface epithelium,
cryptal glands, stroma, and submucosa.