deoxycorticosterone

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de·ox·y·cor·ti·cos·ter·one

 (dē-ŏk′sē-kôr′tĭ-kŏs′tə-rōn′)
n.
A steroid hormone, C21H30O3, secreted by the adrenal cortex or produced synthetically and formerly used to treat adrenal insufficiency.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

deoxycorticosterone

(diːˌɒksɪˌkɔːtɪkəʊˈstɪərəʊn) or

deoxycortone

n
(Biochemistry) a corticosteroid hormone important in maintaining sodium and water balance in the body
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

de•ox•y•cor•ti•cos•ter•one

(diˌɒk sɪˌkɔr tɪˈkɒs təˌroʊn, -ˌkoʊ stəˈroʊn)

n.
a steroid hormone, C21H30O3, secreted by the adrenal cortex, related to corticosterone, and involved in water and electrolyte balance.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
Translations

de·ox·y·cor·ti·co·ster·one

n. desoxicorticosterona, hormona producida en la corteza de las glándulas suprarrenales de efecto marcado en el metabolismo del agua y los electrólitos.
English-Spanish Medical Dictionary © Farlex 2012
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References in periodicals archive
Increased ACTH causes hypokalemia, fluid retention, and hypertension as a consequence of deoxycorticosterone excess.
Niemann et al., "Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension," Hypertension, vol.
Typical characteristics of women with the lack of 17OH are primary amenorrhea, high levels of FSH, LH, progesterone, deoxycorticosterone, hypertension and hyperpotassium alkalosis.
Table 1: Results of hormonal evaluation Patient's Female reference range value (follicular phase) Luteinizing hormone 56 1.9-9.2 U/L Follicle-stimulating hormone 145 3.5-9.2 U/L Estradiol <9.0 18-147 pg/mL Testosterone <0.02 0.084-0.481 ng/mL Dehydroepiandrosterone sulfate <2.5 98.8-340 [micro]g/dL Progesterone 5.8 0.25-0.54 ng/mL 17-OH progesterone <10 20-100 ng/dL Cortisol 0.9 5.4-28.7 [micro]g/dL Adrenocorticotropic hormone 185 6-76 pg/mL Deoxycorticosterone 54 2-19 ng/dL Aldosterone (supine) 0.5 2-9 ng/dL Plasma renin activity (supine) 0.1 0.2-1.6 ng/mL/h Anti-Mullerian hormone <0.2 For female: 1-10 ng/mL For male: 0.7-20 ng/mL
Protection against deoxycorticosterone acetate-salt-induced hypertension and cardiovascular hypertrophy.
Methods: Hypertension was induced in mice by surgical removal of a kidney and by subcutaneous administration of a pellet with deoxycorticosterone. Vasodilatation was measured in mesenteric arteries with a wire myograph.
In adrenals, Pcan be converted either into deoxycorticosterone under the control of 21-hydroxylase or 17-OHP by 17, 20 lyase.
Malignant hypertension resulting from deoxycorticosterone acetate and salt excess.
It addresses the prevalence and risk; the measurement of blood pressure; primary hypertension pathogenesis, natural history, and evaluation; the management of hypertension; treatment through lifestyle modifications and drug therapy; hypertensive emergencies; renal parenchymal and renovascular hypertension; primary aldosteronism; pheochromocytoma; hypertension induced by cortisol or deoxycorticosterone; other forms of hypertension; and hypertension in pregnancy, childhood, and adolescence and in the context of the birth control pill.
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