Quantification of riboflavin,
flavin mononucleotide, and flavin adenine dinucleotide in human plasma by capillary electrophoresis and laser-induced fluorescence detection.
(16) showed that the sum of erythrocyte
flavin mononucleotide and FAD is correlated with the EGRAC and might be a useful indicator of riboflavin status in population studies.
Riboflavin serves as a precursor for
flavin mononucleotide (FMN) and FAD (11).
In contrast, neither plasma
flavin mononucleotide nor plasma flavin adenine dinucleotide showed a relationship with dietary riboflavin, neither were they related to EGRAC or plasma riboflavin.
For the determination of vitamin [B.sub.2] status, plasma concentrations of riboflavin and flavin nucleotides (FNs; i.e., the combined concentration of the coenzymes FAD and
flavin mononucleotide) were determined by a modified HPLC method; CVs were <6% and <4%, respectively (15).
Riboflavin [4] is the precursor of
flavin mononucleotide (FMN) and FAD (1).