Glucagonoma is one of the rare pancreatic neuroendocrine tumors, accounting for only 5% of all cancers of this organ [1].
The common types of functional NETs include carcinoid, insulinoma, gastrinoma,
glucagonoma, VIPoma, and somatostatinoma.
These include insulinoma, gastrinoma, VIPoma, somatostatinoma, and
glucagonoma. Each of these tumors produces the hormone that is its namesake.
Various typical symptoms can be seen related to carcinoid syndrome, Zollinger-Ellison syndrome, Whipple's triad, Verner-Morrison syndrome, insulinoma, and
glucagonoma (11).
"Did you see the
glucagonoma on Sefton 6?" a resident would ask.
Hacker, "Immunohistochemical assessment of an asymptomatic
glucagonoma in a patient with hypergastrinemia and marked antral angiodysplasia," Applied Immunohistochemistry & Molecular Morphology, vol.
and
glucagonoma due to inactivating mutations in the glucagon receptor
carcinoids, gastrinoma,
glucagonoma, VIPoma, etc.), functioning and non-functioning; sympathoadrenal system tumours; pituitary adenoma; medulloblastoma; Merkel cell carcinoma; small-cell lung cancer (mainly primary tumours) and meningioma.
(8.) The medical subject Headings indexing system refers to "islet cell carcinoma", which is subdivided into gastrinoma,
glucagonoma, somatostatinoma and VIPoma.
carcinoids, gastrinoma, insulinoma,
glucagonoma, VIPoma, etc.) Sarcoma Renal cell carcinoma Medullary thyroid Differentiated carcinoma thyroid carcinoma Pituitary adenoma Astrocytoma Merkel cell carcinoma Meningioma Small-cell lung cancer Standard anatomical techniques, such as CT and MRI, are routinely used for staging and restaging of NETs, with an overall sensitivity of 50 - 80%, depending on the size and site of metastatic lesions and the imaging protocol.
Differential diagnosis includes epidermolysis bullosa, cystic fibrosis,
glucagonoma syndrome, widespread candidiasis, pellagra, seborrheic dermatitis, hypovitaminoses, atopic dermatitis, celiac disease, and congenital periorificial and palmo-plantar keratoderma (3).